|2||Lions||W 35 - 17|
|1||@Saints||L 3 - 38|
|2021||Green Bay Packers||1||0|
- Earned second-team All-Atlantic Coast Conference honors in 2020 after ranking No. 5 in the nation and No. 2 in the ACC with a career-best 107 tackles (54 solo).
- According to stathead.com, was one of three players in the FBS to post at least 100 tackles (107), three sacks (three) and six tackles for a loss (6½) in 2020.
- Was a preseason All-ACC selection by Athlon and Phil Steele's College Football, but missed all but the last four games of the 2019 season (starting three) due to injury and earned a redshirt.
- Saw action in all 12 games with six starts at strongside linebacker in 2018, finishing No. 2 on the team with 85 tackles (48 solo).
- Appeared in all 13 games on special teams and earned some playing time at linebacker as a freshman in 2017, finishing with 11 tackles (three solo) and a pass defensed.
- Was a three-time captain as a two-way performer at linebacker and running back at Bennett High School in Buffalo, N.Y., setting school records for single-season tackles (161), single-game tackles (29), career touchdowns (70) and career rushing yards (5,529).
Isaiah McDuffie gained experience against Bills QB Josh Allen
LB Isaiah McDuffie talked about hitting it "full steam ahead" in the Packers' 19-0 loss to the Bills in the preseason finale.
Packers Unscripted: Last call
Mike and Wes preview the final preseason game at Buffalo, discussing what to watch on offense (:24), the competition at safety on defense (8:26), and a special homecoming game for rookie LB Isaiah McDuffie (11:54).
Isaiah McDuffie has trusted the process
Packers LB Isaiah McDuffie talks about getting back to the practice field and getting snaps in the preseason.
Olivadotti on McDuffie: 'Very serious guy, not afraid of a day's hard work'
Packers ILB coach Kirk Olivadotti talks about the progression of rookie LB Isaiah McDuffie, and he discusses Oren Burks switching back to inside linebacker.
McDuffie is 'excited to get everything moving'
Packers LB Isaiah McDuffie spoke to the media following Packers rookie minicamp.
Total Packers: 2021 Draft Report
Join analyst Larry McCarren and writers Mike Spofford and Wes Hodkiewicz as they recap the 2021 NFL Draft.
Packers Daily: May 6
Wayne Larrivee takes a look at Green Bay's newly drafted defenders in this edition of Packers Daily.
Packers Unscripted: Draft debrief, part 2
Mike and Wes discuss the Packers' picks on the third day of the draft, beginning with offensive linemen Royce Newman (:25) and Cole Van Lanen (3:53), continuing with the two fifth-round defenders in LB T.J. Slaton and CB Shemar Jean-Charles (9:30), and concluding with LB Isaiah McDuffie and RB Kylin Hill (17:46).
Three Things: Added competition, special teams, virtual offseason
Wes Hodkiewicz and Larry McCarren break down three things from the Packers' 2021 NFL Draft.
Matt LaFleur 1-on-1: Draft picks can bring instant contribution
Packers Head Coach Matt LaFleur recaps the 2021 NFL Draft with analyst Larry McCarren.
Brian Gutekunst sees mix of immediate contributors and healthy roster competition in Packers' 2021 draft class
Green Bay Packers GM Brian Gutekunst spoke to the media on Saturday following the 2021 NFL Draft.
LaFleur recaps Packers' draft, conveys desire for QB Rodgers to return
Packers Head Coach Matt LaFleur addressed the media following the 2021 NFL Draft.
Isaiah McDuffie: 'Since I touched a football at 7 years old, I knew this is what I wanted to do.'
Packers' sixth-round selection Isaiah McDuffie spoke to the media about getting drafted by the Green Bay Packers.
Instant Reax: Packers add pieces on offensive line and at linebacker in sixth round
Wes Hodkiewicz and Larry McCarren react to the Packers' selection of T/G Cole Van Lanen and LB Isaiah McDuffie in the sixth round of the 2021 NFL Draft.
Isaiah McDuffie ready to return to where it all began
Packers linebacker cherishes memories he shares with his father at Highmark Stadium
5 things learned at Packers training camp – Aug. 24
Rookie safety Innis Gaines goes from DoorDash to NFL doorstep
Isaiah McDuffie brings 'workhorse' mentality as rookie linebacker
Packers' sixth-round draft pick from Boston College doesn't slow down
2021 NFL Draft wrap: Packers got more competitive up and down the roster with their nine picks
A rundown of how the draft class fits in
Packers connections provide foundations for Isaiah McDuffie, Kylin Hill
Green Bay wraps up 2021 draft class with a linebacker and running back